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Structure of 2967-54-6
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3,5-Difluoro-4-hydroxybenzonitrile features a trifunctional aromatic core with electron-withdrawing fluorine atoms and a polar hydroxyl group flanking a nitrile moiety. This combination enables robust participation in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring enhanced metabolic stability and controlled polarity.
3,5-Difluoro-4-hydroxybenzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated aromatic scaffolds. The hydroxyl group facilitates direct derivatization or metal-catalyzed coupling reactions, while the nitrile functions as a handle for amidation or reduction. Its bench-stable nature and orthogonal reactivity profile support streamlined synthesis of bioactive molecules, particularly in kinase inhibitor and CNS-targeted compound development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: