Tetrahydro-2H-thiopyran-4-ol

Name: Tetrahydro-2H-thiopyran-4-ol
Brand: ChemScene
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CAS No. 29683-23-6
Cat. No. CS-D1275
Purity≥97%
MDL No.MFCD02942489

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 29683-23-6

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Description

Tetrahydro-2H-thiopyran-4-ol features a saturated thiopyran ring with a hydroxyl group at the 4-position, delivering a stable, moisture-tolerant scaffold for synthetic applications. The pendant OH group enables selective derivatization, while the sulfur atom imparts moderate polarity and enhanced solubility in organic media. This compound serves as a key building block in heterocyclic synthesis, particularly in the development of bioactive molecules and functional polymers.

Application

Tetrahydro-2H-thiopyran-4-ol serves as a versatile chiral building block in synthetic organic chemistry, offering a readily accessible hydroxyl group at the C4 position of a saturated thiopyran ring. Its bench-stable nature and compatibility with standard protecting group strategies enable efficient functionalization. The molecule facilitates stereoselective transformations and functions as a key intermediate in the synthesis of sulfur-containing heterocycles and bioactive scaffolds.

General Information

CAS No. 29683-23-6
Cat. No. CS-D1275
Purity ≥97%
MDL No. MFCD02942489
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₀OS
Molecular Weight 118.20
Synonym(s) 4-Hydroxythiane
SMILES OC1CCSCC1

Computational Chemistry Data

TPSA 20.23
LogP 0.8743
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS07,GHS09
Signal Word : Danger	UN#: 3077
Class : 9	Packing Group : Ⅲ
Hazard Statements : H302-H318-H410
Precautionary Statements : P273-P280-P391-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Key Words

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Tetrahydro-2H-thiopyran-4-ol

CAS No. 29683-23-6

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