(1,4-Dioxan-2-yl)methanol

Name: (1,4-Dioxan-2-yl)methanol
Brand: ChemScene
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CAS No. 29908-11-0
Cat. No. CS-0130467
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

This bench-stable, moisture-tolerant building block features a dioxane ring fused to a primary alcohol, enabling straightforward functionalization. The acyclic methanol moiety integrates readily into synthetic sequences requiring oxygen-directed reactivity or protecting group strategies.

Application

(1,4-Dioxan-2-yl)methanol serves as a stable, bench-ready synthon for the introduction of 1,4-dioxane motifs into complex molecules. Its hydroxymethyl functionality enables direct functionalization or derivatization in standard synthetic workflows, while the dioxane ring provides robust metabolic stability and favorable solubility properties. The compound exhibits excellent functional group tolerance and facilitates efficient incorporation into heterocyclic scaffolds relevant to medicinal chemistry and process-scale synthesis.

General Information

CAS No. 29908-11-0
Cat. No. CS-0130467
Purity ≥95%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₀O₃
Molecular Weight 118.13
Synonym(s) p-Dioxanemethanol
SMILES OCC1OCCOC1

Computational Chemistry Data

TPSA 38.69
LogP -0.6059
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Key Words

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(1,4-Dioxan-2-yl)methanol

CAS No. 29908-11-0

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