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Structure of 2995-45-1
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1-Nitro-3-(trifluoromethoxy)benzene features a para-nitro group flanked by a trifluoromethoxy substituent, delivering enhanced electron-withdrawing character. This configuration supports stable coupling reactions and facilitates functionalization in synthetic routes to pharmaceutical intermediates and agrochemicals.
1-Nitro-3-(trifluoromethoxy)benzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted aromatic scaffolds. Its trifluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the nitro functionality facilitates sequential transformations including reduction to an amine, electrophilic substitution, or participation in transition-metal-catalyzed couplings. The compound exhibits excellent bench stability and is readily purified by recrystallization, supporting scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: