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CS-W001157 4
Total: USD 88.00

6-Isothiocyanato-Fluorescein

  • CAS No. 3012-71-3

  • Cat. No. CS-0646343
  • Purity≥90%
  • MDL No.MFCD00005063
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Isothiocyanato-Fluorescein|CS-0646343

Structure of 3012-71-3

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Description

6-Isothiocyanato-Fluorescein features a reactive isothiocyanate group enabling direct conjugation to primary amines under mild conditions. This fluorescent probe delivers bright emission with high quantum yield, ideal for labeling biomolecules in immunoassays and live-cell imaging.

Application

6-Isothiocyanato-Fluorescein serves as a versatile fluorescent labeling reagent, enabling efficient conjugation to primary amines under mild conditions. Its isothiocyanate group exhibits high reactivity with amine functionalities, facilitating site-specific bioconjugation in antibody–drug conjugates and protein labeling. The molecule combines strong fluorescence with excellent bench stability and straightforward purification, making it ideal for diagnostic assay development and flow cytometry applications.

General Information

  • CAS No. 3012-71-3
  • Cat. No. CS-0646343
  • Purity ≥90%
  • MDL No. MFCD00005063
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₁NO₅S
  • Molecular Weight 389.38
  • Synonym(s) FITC Isomer Ⅱ
  • SMILES O=C(O)C1=CC=C(N=C=S)C=C1C2=C3C=CC(C=C3OC4=C2C=CC(O)=C4)=O

Computational Chemistry Data

  • TPSA   100.1
  • LogP   4.7029
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H334-H335
Precautionary Statements : P261-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P362+P364-P405-P501

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