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Structure of 3012-80-4
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1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde features a rigid, electron-deficient heteroaromatic core with a pendant aldehyde group. This configuration enables direct coupling in Ullmann-type reactions and facilitates incorporation into bioactive scaffolds requiring polar, planar functionalities. The methyl substituent enhances solubility and stabilizes the imidazole ring under standard conditions.
1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its formyl group enables direct incorporation into imine, hydrazone, and amidine derivatives via standard condensation reactions. The benzoimidazole core offers enhanced metabolic stability and π-stacking potential, while the N-methyl substituent improves solubility and reduces basicity compared to the parent scaffold. Bench-stable and readily purified by flash chromatography, it functions efficiently in multistep syntheses of bioactive molecules and functionalized aromatic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: