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CS-W001157 4
Total: USD 88.00

Boc-N-PEG2-MS

  • CAS No. 302331-20-0

  • Cat. No. CS-0114469
  • Purity≥98%
  • MDL No.MFCD24465573

*For research and further manufacturing use only, not for direct human use.

Boc-N-PEG2-MS|CS-0114469

Structure of 302331-20-0

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General Information

  • CAS No. 302331-20-0
  • Cat. No. CS-0114469
  • Purity ≥98%
  • MDL No. MFCD24465573
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁NO₆S
  • Molecular Weight 283.34
  • Synonym(s) None
  • SMILES CS(OCCOCCNC(OC(C)(C)C)=O)(=O)=O

Description

Boc-N-PEG2-MS features a tert-butoxycarbonyl-protected amine linked to a two-unit polyethylene glycol spacer, terminating in a maleimide group. This bifunctional reagent enables site-specific conjugation via Michael addition with thiol-containing biomolecules, offering enhanced solubility and stability in aqueous environments.

Application

Boc-N-PEG2-MS serves as a versatile bifunctional linker for peptide and small-molecule conjugation, enabling efficient N-terminal functionalization via its maleimide group. The Boc-protected amine ensures stability during storage and handling, while the PEG2 spacer provides enhanced solubility and reduced steric hindrance. This reagent facilitates site-specific bioconjugation in aqueous media and is compatible with standard purification methods, making it ideal for synthesizing antibody-drug conjugates and targeted delivery systems.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   90.93
  • LogP   0.5039
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   7

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