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Structure of 3057-74-7
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L-Aspartic acid 4-tert-butyl ester features a sterically shielded tert-butyl group that enhances stability and simplifies purification. This protected derivative enables efficient incorporation into peptide syntheses, offering improved handling under standard conditions while maintaining compatibility with orthogonal deprotection strategies.
L-Aspartic acid 4-tert-butyl ester serves as a key chiral building block in peptide synthesis, offering enhanced solubility and stability compared to the free acid. The tert-butyl ester group provides orthogonal protection for the C-terminal carboxylate, enabling selective coupling reactions under standard Fmoc-based protocols. Its well-established reactivity facilitates efficient incorporation into peptide sequences and heterocyclic scaffolds, with predictable deprotection via mild acid treatment.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: