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Structure of 306937-12-2
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This tert-butyl ester-functionalized benzoic acid derivative features a methoxy group at the para position and a protected amine via Boc, enabling selective deprotection and coupling in peptide synthesis. The combination of electron-donating methoxy and sterically shielded Boc moiety enhances stability under standard conditions, streamlining incorporation into complex molecular architectures.
3-(tert-Butoxycarbonylamino)-4-methoxybenzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and peptide-conjugated scaffolds. Its orthogonal functionality—tolerant to standard coupling conditions—enables selective derivatization of the carboxylic acid and amine groups, facilitating efficient access to diverse pharmacophores via amidation, esterification, or cyclization reactions. The tert-butoxycarbonyl (Boc) group provides robust protection under acidic conditions, while the methoxy substituent enhances solubility and modulates electronic effects in subsequent transformations.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: