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Structure of 306937-14-4
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tert-Butyl (4-bromo-2-methylphenyl)carbamate features a brominated, methyl-substituted phenyl scaffold with a robust tert-butyl carbamate protecting group. This combination enables stable incorporation into complex synthetic sequences, particularly in late-stage functionalization and transition-metal-catalyzed coupling processes. The electron-deficient aryl moiety enhances reactivity in palladium-mediated transformations, while the bench-stable protecting group simplifies handling and purification.
tert-Butyl (4-bromo-2-methylphenyl)carbamate serves as a versatile building block in medicinal chemistry, enabling the introduction of a brominated aniline moiety with orthogonal protection. The carbamate group offers excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. Its compatibility with palladium-catalyzed cross-coupling reactions allows efficient construction of biaryl scaffolds, while the methyl and bromo substituents provide defined regiochemistry for further functionalization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: