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Structure of 30955-94-3
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1-(5-Iodothiophen-2-yl)ethanone features a thiophene ring functionalized with an iodine atom at the 5-position and a ketone group at the 2-position, enabling direct coupling in cross-coupling reactions. The electron-deficient thiophene core enhances reactivity in palladium-catalyzed transformations, while the bench-stable ketone provides a handle for further derivatization.
1-(5-Iodothiophen-2-yl)ethanone serves as a versatile building block for cross-coupling reactions, enabling efficient access to functionalized biaryl and heteroaryl architectures. Its iodine moiety facilitates palladium-catalyzed coupling with arylboranes, alkenylstannanes, and other nucleophiles under standard conditions. The ketone group provides additional synthetic handle for further transformations, including reduction or nucleophilic addition. Bench-stable and readily purified by crystallization, it supports scalable synthesis of pharmaceutical intermediates and advanced materials.
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GHS Pictogram :
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H315-H319-H334-H335
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Precautionary Statements : P261-P264-P271-P280-P284-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: