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CS-W001157 4
Total: USD 88.00

Bis-PEG4-acid

  • CAS No. 31127-85-2

  • Cat. No. CS-0068187
  • Purity≥98%
  • MDL No.MFCD22201545

*For research and further manufacturing use only, not for direct human use.

Bis-PEG4-acid|CS-0068187

Structure of 31127-85-2

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General Information

  • CAS No. 31127-85-2
  • Cat. No. CS-0068187
  • Purity ≥98%
  • MDL No. MFCD22201545
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂O₈
  • Molecular Weight 294.30
  • Synonym(s) None
  • SMILES OC(CCOCCOCCOCCOCCC(O)=O)=O

Description

Bis-PEG4-acid features two carboxylic acid termini flanking a central PEG4 spacer, enabling efficient conjugation in aqueous environments. This bifunctional linker combines excellent solubility with stability under standard bench conditions, facilitating robust coupling reactions in biomolecule labeling and polymer synthesis.

Application

Bis-PEG4-acid serves as a versatile bifunctional linker for conjugation and polymer synthesis, offering excellent solubility and stability in aqueous and organic media. Its two terminal carboxylic acid groups enable efficient coupling with amines via amide bond formation, while the PEG4 spacer provides enhanced solubility and reduced non-specific binding. Widely used in bioconjugation, drug delivery systems, and surface functionalization, it facilitates precise spatial control and improved pharmacokinetic properties in advanced molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   111.52
  • LogP   0.0022
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   15

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