(R)-2-Hydroxy-2-(p-tolyl)acetic acid

Name: (R)-2-Hydroxy-2-(p-tolyl)acetic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 31284-89-6
Cat. No. CS-0186127
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-Hydroxy-2-(p-tolyl)acetic acid|CS-0186127

Structure of 31284-89-6

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Description

(R)-2-Hydroxy-2-(p-tolyl)acetic acid features a chiral α-hydroxy carboxylic acid scaffold with a para-tolyl group enhancing electronic stability and solubility. This bench-stable, moisture-tolerant reagent integrates readily into asymmetric synthesis workflows, serving as a key chiral auxiliary for stereoselective transformations.

Application

(R)-2-Hydroxy-2-(p-tolyl)acetic acid serves as a valuable chiral building block in asymmetric synthesis, enabling the construction of biologically relevant scaffolds through established enantioselective transformations. Its bench-stable nature and well-defined stereochemistry facilitate reliable use in medicinal chemistry and process development. The molecule functions effectively in coupling reactions and acts as a precursor to α-hydroxy carboxylic acid derivatives with high synthetic utility.

General Information

CAS No. 31284-89-6
Cat. No. CS-0186127
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀O₃
Molecular Weight 166.17
Synonym(s) (R)-4-Methylmandelic acid
SMILES CC1=CC=C(C=C1)[C@H](C(=O)O)O

Computational Chemistry Data

TPSA 57.53
LogP 1.11302
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501

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Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-Hydroxy-2-(p-tolyl)acetic acid

CAS No. 31284-89-6

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