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Structure of 313546-19-9
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This boronate moiety features a cyano-substituted aryl group with enhanced electron-withdrawing character, enabling efficient cross-coupling reactions. The methyl group at the ortho position provides steric stabilization and improves bench stability. This compound integrates readily into complex molecular architectures under standard conditions, offering high functional group tolerance and reliable reactivity in Suzuki-Miyaura coupling processes.
(3-Cyano-2-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds with high functional group tolerance. The ortho-cyano and methyl groups enhance regioselectivity and electronic modulation in cross-coupling, while the boronic acid moiety offers excellent bench stability and ease of purification. This reagent is well-suited for the synthesis of heterocyclic intermediates and advanced pharmaceutical precursors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: