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Structure of 31462-54-1
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2-Iodopyrimidine features a reactive iodine atom at the C2 position, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. The electron-deficient pyrimidine ring enhances regioselectivity, while its bench-stable nature supports reliable handling under standard conditions. This compound serves as a key scaffold for synthesizing biologically active heterocycles and advanced pharmaceutical intermediates.
2-Iodopyrimidine serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura, Stille, and Negishi couplings. Its iodine substituent provides high reactivity under standard conditions, facilitating efficient C–C bond formation with aryl, vinyl, and alkyl boron reagents. The pyrimidine core offers excellent functional group tolerance and stability, making it suitable for the synthesis of heterocyclic scaffolds commonly found in pharmaceuticals and agrochemicals.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: