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Structure of 315-53-7
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4-Fluoronaphthalen-1-ol offers a strategic fusion of aromatic rigidity and polar functionality, enabling direct incorporation into bioactive scaffolds. The para-fluorine enhances metabolic stability while the phenolic hydroxyl facilitates hydrogen bonding and downstream derivatization. This bench-stable compound serves as a key intermediate in pharmaceutical and agrochemical synthesis.
4-Fluoronaphthalen-1-ol serves as a versatile building block for the synthesis of functionalized naphthalene scaffolds, enabling direct electrophilic substitution and palladium-catalyzed coupling reactions. The ortho-fluoro substitution facilitates selective C–H activation, while the phenolic hydroxyl group offers sites for derivatization or protection. Its bench-stable crystalline form simplifies handling and purification in synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: