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CS-W001157 4
Total: USD 88.00

(2,4-Difluoro-5-methylphenyl)methanol

  • CAS No. 315204-46-7

  • Cat. No. CS-0378729
  • Purity≥98%
  • MDL No.MFCD12196966

*For research and further manufacturing use only, not for direct human use.

(2,4-Difluoro-5-methylphenyl)methanol|CS-0378729

Structure of 315204-46-7

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General Information

  • CAS No. 315204-46-7
  • Cat. No. CS-0378729
  • Purity ≥98%
  • MDL No. MFCD12196966
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈F₂O
  • Molecular Weight 158.15
  • Synonym(s) Benzenemethanol,2,4-difluoro-5-methyl
  • SMILES OCC1=CC(C)=C(F)C=C1F

Synthesis

  • Route1
    • Methyl 2,4-difluoro-5-methylbenzoate|CS-0533668
      1162674-66-9
    • ~99%
    • (2,4-Difluoro-5-methylphenyl)methanol|CS-0378729
      315204-46-7

    References

    • CONFLUENCE LIFE SCIENCES, INC.; SELNESS, Shaun R.; Devadas, Balekudru; Hockerman, Susan L.; Monahan, Joseph B. Patent: US2013/143906 A1, 2013 ; Location in patent: Paragraph 0330 ;
  • Route2
    • 2,4-Difluoro-5-methylbenzaldehyde|CS-W007000
      315204-36-5
    • ~78%
    • (2,4-Difluoro-5-methylphenyl)methanol|CS-0378729
      315204-46-7

    References

    • Wang, Zhi-Xian; Duan, Weili; Wiebe, Leonard I.; De Clercq, Erik; Balzarini, Jan; Knaus, Edward E. Nucleosides, Nucleotides and Nucleic Acids, 2000 , vol. 19, # 9 p. 1397 - 1411
  • Route3

    References

    • CONFLUENCE LIFE SCIENCES, INC.; SELNESS, Shaun R.; Devadas, Balekudru; Hockerman, Susan L.; Monahan, Joseph B. Patent: US2013/143906 A1, 2013 ;

Safety Information

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Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.76552
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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