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Structure of 31575-35-6
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2-Fluoropyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, offering enhanced metabolic stability and improved binding affinity in kinase inhibitors. This electron-deficient pyrimidine derivative integrates readily into bioactive molecules, enabling efficient coupling reactions under standard conditions.
2-Fluoropyrimidine serves as a versatile building block in medicinal chemistry, enabling site-specific functionalization via nucleophilic aromatic substitution. Its high reactivity at C5 facilitates efficient coupling with diverse amines and thiols, offering reliable access to substituted pyrimidine scaffolds. The fluorine atom enhances metabolic stability and modulates electronic properties, making it valuable for drug discovery. Bench-stable and readily purified, it functions effectively in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H226-H302-H315-H318-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: