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CS-W001157 4
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Methyl 5-chloro-6-oxo-1,6-dihydropyridine-3-carboxylate

  • CAS No. 316166-47-9

  • Cat. No. CS-0143681
  • Molecule weight187.58
  • Purity≥97%
  • MDL No.MFCD03844853

*For research and further manufacturing use only, not for direct human use.

Methyl 5-chloro-6-oxo-1,6-dihydropyridine-3-carboxylate|CS-0143681

Structure of 316166-47-9

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General Information

  • CAS No. 316166-47-9
  • Cat. No. CS-0143681
  • Purity ≥97%
  • MDL No. MFCD03844853
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆ClNO₃
  • Molecular Weight 187.58
  • Synonym(s) Methyl 5-chloro-6-oxo-1,6-dihydro-3-pyridinecarboxylate
  • SMILES O=C(OC)C(C=C1Cl)=CNC1=O

Synthesis

  • Route1
    • null|null
      67-56-1
    • 5-Chloro-6-oxo-1,6-dihydropyridine-3-carboxylic acid Avatrombopag Impurity|CS-0377312
      54127-63-8
    • ~56%
    • In-stock
      Methyl 5-chloro-6-oxo-1,6-dihydropyridine-3-carboxylate|CS-0143681
      316166-47-9

    References

    • F. HOFFMANN-LA ROCHE AG; BENSON, Gregory Martin; BLEICHER, Konrad; FENG, Song; GRETHER, Uwe; KUHN, Bernd; MARTIN, Rainer E.; PLANCHER, Jean-Marc; RICHTER, Hans; TAYLOR, Sven Patent: WO2010/28981 A1, 2010 ; Location in patent: Page/Page column 59 ; WO 2010/028981 A1

Safety Information

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Computational Chemistry Data

  • TPSA   59.16
  • LogP   0.8149
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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