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Structure of 3163-27-7
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1-(Bromomethyl)naphthalene features a reactive bromomethyl group appended to the naphthalene scaffold, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. This bench-stable, moisture-tolerant reagent integrates seamlessly into synthetic sequences requiring aromatic alkyl halide intermediates, offering high regiocontrol and compatibility with palladium-catalyzed transformations.
1-(Bromomethyl)naphthalene serves as a versatile benzylating agent in synthetic organic chemistry, enabling efficient introduction of naphthylmethyl groups into diverse substrates. Its bromomethyl functionality reacts reliably with nucleophiles such as amines, thiols, and carbanions under mild conditions, facilitating the construction of biologically relevant scaffolds. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: