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CS-W001157 4
Total: USD 88.00

7-Fluoroisatin

  • CAS No. 317-20-4

  • Cat. No. CS-W009274
  • Purity≥97%
  • MDL No.MFCD01569508

*For research and further manufacturing use only, not for direct human use.

7-Fluoroisatin|CS-W009274

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General Information

  • CAS No. 317-20-4
  • Cat. No. CS-W009274
  • Purity ≥97%
  • MDL No. MFCD01569508
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄FNO₂
  • Molecular Weight 165.12
  • Synonym(s) 7-Fluoroindole-2,3-dione
  • SMILES O=C1NC2=C(C=CC=C2F)C1=O

Description

7-Fluoroisatin delivers a fluorinated isatin scaffold with enhanced electronic properties, enabling efficient integration into bioactive heterocycles. This bench-stable derivative features a strategically positioned fluorine atom that modulates reactivity and metabolic stability in medicinal chemistry applications.

Application

7-Fluoroisatin serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive scaffolds. Its electrophilic carbonyl groups facilitate nucleophilic addition reactions, while the fluorine substituent enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and is compatible with standard coupling and cyclization protocols, making it a practical choice for iterative library synthesis and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   46.17
  • LogP   0.9605
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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