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CS-W001157 4
Total: USD 88.00

4-Bromo-2-fluoro-1-nitrobenzene

  • CAS No. 321-23-3

  • Cat. No. CS-D0900
  • Molecule weight220.00
  • Purity≥97%
  • MDL No.MFCD01930221

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-fluoro-1-nitrobenzene|CS-D0900

Structure of 321-23-3

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General Information

  • CAS No. 321-23-3
  • Cat. No. CS-D0900
  • Purity ≥97%
  • MDL No. MFCD01930221
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrFNO₂
  • Molecular Weight 220.00
  • Synonym(s) Benzene, 4-bromo-2-fluoro-1-nitro-
  • SMILES FC1=CC(Br)=CC=C1[N+]([O-])=O

Description

4-Bromo-2-fluoro-1-nitrobenzene is a trifunctional aromatic building block featuring bromo, fluoro, and nitro groups in a defined ortho/meta substitution pattern. This electron-deficient scaffold enables direct coupling reactions and facilitates downstream functionalization in pharmaceutical synthesis and materials science applications.

Synthesis

  • Route1

    References

    • Liu, Jia; Li, Jue; Ren, Jiangmeng; Zeng, Bu-Bing Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1581 - 1584
  • Route2

    References

    • US2010/280268 A1, ; Page/Page column 22 ;
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 78, p. 6034,6037

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.14
  • LogP   2.4964
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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