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Structure of 321-69-7
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5-Fluoroisatoic anhydride features a highly reactive anhydride moiety flanked by a fluorinated aromatic ring, enabling efficient coupling in heterocyclic synthesis. This bench-stable reagent integrates readily into complex scaffolds under mild conditions, delivering enhanced regioselectivity in the construction of fluorinated indole derivatives and related bioactive architectures.
5-Fluoroisatoic anhydride serves as a versatile building block for the synthesis of fluorinated heterocycles and bioactive scaffolds. Its reactive anhydride functionality enables efficient coupling with amines and alcohols under mild conditions, facilitating rapid access to substituted isoxazoles, quinolines, and other nitrogen-containing frameworks. The fluorine substituent enhances metabolic stability and modulates electronic properties, making it valuable in medicinal chemistry. Bench-stable and readily handled, it offers predictable reactivity and clean purification profiles in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: