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Structure of 32122-09-1
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Ethyl 2-(benzyloxy)acetate is a bench-stable, moisture-tolerant ester featuring a benzyloxy-modified acetic acid backbone. This compound integrates seamlessly into synthetic sequences requiring orthogonal protection strategies. The benzyl ether moiety enables selective deprotection under mild hydrogenolysis conditions, facilitating downstream functionalization in complex molecule assembly.
Ethyl 2-(benzyloxy)acetate serves as a versatile synthetic intermediate for the construction of benzyl-protected glycolate derivatives. It functions as a reliable precursor in the synthesis of β-hydroxy esters and enables direct functionalization at the α-position via enolization. The benzyloxy group provides orthogonal protection compatible with standard deprotection conditions, while the ethyl ester supports broad reactivity in nucleophilic substitutions and coupling reactions. Its bench-stable nature and ease of purification make it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: