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CS-W001157 4
Total: USD 88.00

7-(Trifluoromethyl)quinolin-4-ol

  • CAS No. 322-97-4

  • Cat. No. CS-W014268
  • Purity≥96%
  • MDL No.MFCD00006779

*For research and further manufacturing use only, not for direct human use.

7-(Trifluoromethyl)quinolin-4-ol|CS-W014268

Structure of 322-97-4

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General Information

  • CAS No. 322-97-4
  • Cat. No. CS-W014268
  • Purity ≥96%
  • MDL No. MFCD00006779
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆F₃NO
  • Molecular Weight 213.16
  • Synonym(s) 7-TRIFLUOROMETHYL-4(1H)-QUINOLINONE
  • SMILES OC1=CC=NC2=CC(C(F)(F)F)=CC=C12

Description

4-Hydroxy-7-(trifluoromethyl)quinoline was used in the synthesis of 4[[7-(trifluoromethyl)quinolin-4-yl]oxy]pthalonitrile.

Synthesis

  • Route1
    • Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate|CS-0368607
      391-02-6
    • ~80%
    • In-stock
      7-(Trifluoromethyl)quinolin-4-ol|CS-W014268
      322-97-4

    References

    • PFIZER INC. Patent: WO2005/63739 A1, 2005 ; Location in patent: Page/Page column 45-46 ; WO 2005/063739 A1
  • Route2
    • 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid|CS-0155758
      574-92-5
    • ~%
    • In-stock
      7-(Trifluoromethyl)quinolin-4-ol|CS-W014268
      322-97-4

    References

    • Journal of the American Chemical Society, , vol. 69, p. 371,373
  • Route3
    • null|null
      370-35-4
    • ~%
    • In-stock
      7-(Trifluoromethyl)quinolin-4-ol|CS-W014268
      322-97-4

    References

    • Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.9592
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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