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Structure of 3222-48-8
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5-Cyano-2-picoline features a nitrile group flanked by a methylpyridine scaffold, delivering enhanced electronic withdrawal and improved solubility in polar organic media. This bench-stable heterocycle integrates readily into transition-metal-catalyzed coupling reactions, enabling efficient access to functionalized pyridine derivatives under standard conditions.
5-Cyano-2-picoline serves as a versatile building block in synthetic organic chemistry, enabling efficient access to nitrogen-containing heterocycles and functionalized aromatic scaffolds. Its dual functionality—cyano and pyridine groups—supports diverse transformations including nucleophilic substitution, metal-catalyzed coupling reactions, and directed ortho-metalation. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H318
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Precautionary Statements : P264-P270-P280-P330-P405-P501
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Lot numbers can be found on the outside label of a product: