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Structure of 3222-49-9
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5-Methylnicotinic acid is a bench-stable, electron-rich heteroaromatic carboxylic acid featuring a methyl group at the 5-position of the pyridine ring. This substitution enhances lipophilicity and modulates reactivity in synthetic transformations. The molecule serves as a direct precursor for bioactive alkaloid analogs and functionalized polymers. Its compatibility with standard coupling protocols enables efficient integration into diverse molecular architectures under mild conditions.
5-Methylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-based heterocycles and bioactive scaffolds. Its methyl group enhances lipophilicity and metabolic stability, while the carboxylic acid facilitates straightforward derivatization via amide, ester, or acyl chloride formation. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, making it a practical choice for API intermediate development and high-throughput screening campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352
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Lot numbers can be found on the outside label of a product: