Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Diethyl 3-hydroxyglutarate

  • CAS No. 32328-03-3

  • Cat. No. CS-W015410
  • Purity≥98%
  • MDL No.MFCD00009202

*For research and further manufacturing use only, not for direct human use.

Diethyl 3-hydroxyglutarate|CS-W015410

Structure of 32328-03-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 32328-03-3
  • Cat. No. CS-W015410
  • Purity ≥98%
  • MDL No. MFCD00009202
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆O₅
  • Molecular Weight 204.22
  • Synonym(s) Pentanedioic acid, 3-hydroxy-, diethyl ester
  • SMILES CCOC(=O)CC(O)CC(=O)OCC

Description

Diethyl 3-hydroxyglutarate features a hydroxyl group flanked by two ester functionalities, enabling direct functionalization at the C3 position. This structure supports stereocontrolled synthesis in complex molecule assembly and serves as a key intermediate in the construction of chiral building blocks for pharmaceutical applications.

Application

Diethyl 3-hydroxyglutarate serves as a versatile building block in synthetic organic chemistry, enabling the construction of chiral γ-hydroxy carboxylic acid derivatives and functionalized heterocycles. Its dual ester functionality and α-hydroxy substitution support selective transformations, including stereoselective reductions, derivatizations, and cyclization reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and natural product synthesis.

Synthesis

  • Route1

    References

    • Poldy, Jacqueline; Peakall, Rod; Barrow, Russell A. European Journal of Organic Chemistry, 2012 , # 29 p. 5818 - 5827
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 83, p. 4228 - 4233
  • Route3
    • 3-Hydroxyglutaric acid dimethyl ester|CS-W008294
      7250-55-7
    • ~%
    • In-stock
      Diethyl 3-hydroxyglutarate|CS-W015410
      32328-03-3

    References

    • Journal of the American Chemical Society, , vol. 83, p. 4228 - 4233

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   72.83
  • LogP   0.2537
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   6

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Diethyl 3-hydroxyglutarate sigmaDiethyl 3-hydroxyglutarate manufacturerDiethyl 3-hydroxyglutarate priceDiethyl 3-hydroxyglutarate structureDiethyl 3-hydroxyglutarate SDSbuy Diethyl 3-hydroxyglutarateDiethyl 3-hydroxyglutarate supplierDiethyl 3-hydroxyglutarate usesDiethyl 3-hydroxyglutarate molecular weightprice of Diethyl 3-hydroxyglutarateDiethyl 3-hydroxyglutarate chemical name formula of Diethyl 3-hydroxyglutarate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label