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Structure of 324-41-4
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2-Bromo-6-fluoronaphthalene is a halogenated naphthalene derivative featuring complementary reactive sites for cross-coupling and functionalization. The bromine at position 2 enables palladium-catalyzed coupling, while the fluorine at position 6 offers orthogonal reactivity and enhanced metabolic stability. This dual functionality supports efficient synthesis of complex aromatic architectures in medicinal chemistry and materials science.
2-Bromo-6-fluoronaphthalene serves as a versatile building block in cross-coupling reactions, enabling efficient C–C bond formation under palladium catalysis. Its ortho-halogenated naphthalene framework provides excellent regiocontrol and functional group tolerance, facilitating the synthesis of biaryl systems and complex heterocycles. The compound exhibits good bench stability and is readily purified by distillation or recrystallization, making it well-suited for scalable medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: