2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid

Name: 2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid
Brand: ChemScene
Availability: InStock
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CAS No. 32595-59-8
Cat. No. CS-W016853
Purity≥98%
MDL No.MFCD00067304

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid|CS-W016853

Structure of 32595-59-8

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Description

This amino acid derivative features a thiophene ring directly linked to the alpha carbon, enhancing electronic conjugation and metabolic stability. The adjacent hydroxyl and amino groups enable versatile functionalization in peptide synthesis and chemical biology applications.

Application

2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid serves as a versatile building block for heterocyclic synthesis and peptide-like scaffolds, featuring a chiral α-amino acid core with orthogonal functional groups. The hydroxyl and carboxylic acid moieties enable selective derivatization, while the thiophene ring imparts electronic and steric influence beneficial in medicinal chemistry. Bench-stable and compatible with standard purification methods, it facilitates efficient access to bioactive motifs through established coupling and cyclization protocols.

General Information

CAS No. 32595-59-8
Cat. No. CS-W016853
Purity ≥98%
MDL No. MFCD00067304
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₉NO₃S
Molecular Weight 187.21
Synonym(s) None
SMILES NC(C(O)C1=CC=CS1)C(O)=O

Computational Chemistry Data

TPSA 83.55
LogP 0.1934
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 3

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Serine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

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2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid

CAS No. 32595-59-8

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