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Structure of 3282-56-2
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1-(Tert-butyl)-4-nitrobenzene features a para-nitro group flanked by a sterically hindered tert-butyl substituent, delivering enhanced stability and solubility in organic media. This electronic modulation enables efficient incorporation into synthetic routes requiring electron-deficient aromatic intermediates.
1-(Tert-butyl)-4-nitrobenzene serves as a robust synthetic building block for nitroarene functionalization, enabling selective reduction to the corresponding aniline derivative under standard conditions. Its tert-butyl group provides steric protection and enhances solubility in organic media, facilitating purification and handling. The molecule exhibits excellent bench stability and compatibility with common coupling reactions, making it a practical intermediate for constructing substituted benzene scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: