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Structure of 32858-93-8
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2-(Trifluoromethoxy)phenol features a trifluoromethoxy group flanking a phenolic hydroxyl, delivering enhanced electron-withdrawal and metabolic stability. This combination imparts high lipophilicity and resistance to oxidative degradation, making it valuable for medicinal chemistry applications requiring robust aromatic scaffolds in bioactive molecule design.
2-(Trifluoromethoxy)phenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the phenolic hydroxyl group. Its trifluoromethoxy substituent imparts enhanced metabolic stability and lipophilicity, while the ortho-orientation facilitates intramolecular interactions in target-directed design. The compound exhibits good bench stability and compatibility with standard coupling reactions, facilitating efficient access to fluorinated heterocycles and bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H317-H319-H412
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: