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CS-W001157 4
Total: USD 88.00

2-(Bromoacetyl)-1,3-thiazole

  • CAS No. 3292-77-1

  • Cat. No. CS-D0891
  • Purity≥96%
  • MDL No.MFCD06411540

*For research and further manufacturing use only, not for direct human use.

2-(Bromoacetyl)-1,3-thiazole|CS-D0891

Structure of 3292-77-1

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General Information

  • CAS No. 3292-77-1
  • Cat. No. CS-D0891
  • Purity ≥96%
  • MDL No. MFCD06411540
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BrNOS
  • Molecular Weight 206.06
  • Synonym(s) 2-Bromo-1-(thiazol-2-yl)ethanone
  • SMILES O=C(CBr)C1=NC=CS1

Description

2-(Bromoacetyl)-1,3-thiazole features a reactive bromoacetyl group tethered to a heteroaromatic thiazole core, enabling site-specific conjugation in synthetic workflows. This bench-stable reagent integrates readily into peptide and small-molecule derivatization, offering high chemoselectivity under mild conditions.

Application

2-(Bromoacetyl)-1,3-thiazole serves as a versatile bifunctional building block in synthetic organic chemistry, enabling efficient C–C and C–N bond formation. The bromoacetyl group exhibits high reactivity toward nucleophiles, facilitating rapid functionalization under mild conditions. Its stability under standard bench handling and compatibility with diverse functional groups make it ideal for constructing heterocyclic scaffolds, peptide conjugates, and advanced intermediates in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.7207
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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