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Structure of 3297-72-1
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1-Phenylisoquinoline is a nitrogen-rich heterocyclic scaffold featuring a fused benzene and pyridine ring system with a phenyl substituent at the isoquinoline nitrogen. This structure imparts enhanced π-conjugation and electron density, enabling effective integration into organic semiconductors, photoredox catalysts, and bioactive molecules. The compound exhibits good solubility in common organic solvents and stability under ambient conditions, facilitating handling in synthetic workflows.
1-Phenylisoquinoline serves as a versatile heterocyclic scaffold in medicinal chemistry and materials science, enabling efficient access to bioactive molecules through palladium-catalyzed cross-coupling reactions. Its electron-rich aromatic system facilitates functionalization at multiple positions, while its structural rigidity enhances target binding affinity. The compound exhibits good bench stability and is readily purified by column chromatography, making it well-suited for iterative synthesis workflows in API development and probe design.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: