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CS-W001157 4
Total: USD 88.00

1H-Pyrazole-3-carboxamide

  • CAS No. 33064-36-7

  • Cat. No. CS-W006006
  • Purity≥98%
  • MDL No.MFCD11036164

*For research and further manufacturing use only, not for direct human use.

1H-Pyrazole-3-carboxamide|CS-W006006

Structure of 33064-36-7

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General Information

  • CAS No. 33064-36-7
  • Cat. No. CS-W006006
  • Purity ≥98%
  • MDL No. MFCD11036164
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅N₃O
  • Molecular Weight 111.10
  • Synonym(s) Pyrazole-3-carboxamide
  • SMILES O=C(C1=NNC=C1)N

Description

1H-Pyrazole-3-carboxamide features a fused heterocyclic core with a carboxamide group at the 3-position, enabling robust hydrogen bonding and dipolar interactions. This scaffold integrates readily into bioactive molecules, offering enhanced solubility and metabolic stability in medicinal chemistry applications.

Application

1H-Pyrazole-3-carboxamide serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds. Its amide functionality offers enhanced solubility and hydrogen-bonding capacity, while the pyrazole core provides metabolic stability and favorable pharmacokinetic properties. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating straightforward derivatization for target-directed synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   71.77
  • LogP   -0.4914
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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