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Structure of 331647-04-2
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8-Bromo-2-chloroquinazolin-4(3H)-one features a fused heterocyclic core bearing bromo and chloro substituents at the 8- and 2-positions, respectively. This electron-deficient scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibition and DNA intercalation. The molecule exhibits enhanced metabolic stability and favorable solubility profiles under standard conditions.
8-Bromo-2-chloroquinazolin-4(3H)-one serves as a versatile heterocyclic building block for medicinal chemistry campaigns, enabling direct functionalization at C8 and C2 positions. Its stability under standard reaction conditions facilitates palladium-catalyzed cross-coupling, nucleophilic substitution, and further derivatization in the synthesis of kinase inhibitors and other bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: