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CS-W001157 4
Total: USD 88.00

2,5-Dimethoxy-2,5-dihydrofuran

  • CAS No. 332-77-4

  • Cat. No. CS-W016547
  • Purity≥95%
  • MDL No.MFCD00003220

*For research and further manufacturing use only, not for direct human use.

2,5-Dimethoxy-2,5-dihydrofuran|CS-W016547

Structure of 332-77-4

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General Information

  • CAS No. 332-77-4
  • Cat. No. CS-W016547
  • Purity ≥95%
  • MDL No. MFCD00003220
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₃
  • Molecular Weight 130.14
  • Synonym(s) 2,5-Dimethoxy-2,5-dihydrofuran, mixture ofcis and trans
  • SMILES COC1C=CC(OC)O1

Description

2,5-Dimethoxy-2,5-dihydrofuran serves as a stable, bench-ready synthon for heterocyclic scaffold construction. Featuring two methoxy groups flanking a labile dihydrofuran ring, it enables selective functionalization under mild conditions. The electron-rich framework facilitates coupling reactions and acts as a masked 1,4-dicarbonyl equivalent in synthetic sequences.

Application

2,5-Dimethoxy-2,5-dihydrofuran serves as a versatile dihydrofuran scaffold for heterocyclic synthesis, offering predictable regioselective reactivity in electrophilic functionalization and transition-metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with common protecting group strategies facilitate integration into complex molecule assembly workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302+H332-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P304+P340-P330-P370+P378-P501

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   0.5178
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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