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Structure of 332187-56-1
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3,3-Dimethoxycyclobutanecarboxylic acid features a rigid cyclobutane core bearing two methoxy groups at the geminal 3-position, enhancing solubility and metabolic stability. This electron-rich scaffold integrates readily into bioactive molecules, serving as a constrained isostere for carboxylic acid-containing pharmacophores in medicinal chemistry applications.
3,3-Dimethoxycyclobutanecarboxylic acid serves as a stable, bench-ready building block for cyclobutane-based scaffolds in medicinal chemistry. The geminal dimethoxy group enhances solubility and provides a handle for selective deprotection or derivatization. It functions effectively in esterification, amidation, and coupling reactions, enabling access to diverse cyclobutanecarboxylate derivatives with predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: