Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Hydroxyisophthalaldehyde

  • CAS No. 3328-69-6

  • Cat. No. CS-W016326
  • Purity≥97%
  • MDL No.MFCD00839420

*For research and further manufacturing use only, not for direct human use.

2-Hydroxyisophthalaldehyde|CS-W016326

Structure of 3328-69-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 3328-69-6
  • Cat. No. CS-W016326
  • Purity ≥97%
  • MDL No. MFCD00839420
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆O₃
  • Molecular Weight 150.13
  • Synonym(s) 2-hydroxybenzene-1,3-dicarbaldehyde
  • SMILES OC1=C(C=O)C=CC=C1C=O

Description

2-Hydroxyisophthalaldehyde features a strategically positioned aldehyde and hydroxyl group on a benzene ring, enabling dual functionalization in synthetic transformations. This ortho-configured scaffold facilitates chelation and cyclization reactions, supporting efficient construction of heterocyclic architectures under mild conditions.

Application

2-Hydroxyisophthalaldehyde serves as a versatile bifunctional building block for the synthesis of heterocycles and chelating ligands. Its ortho-hydroxyl and aldehyde groups enable efficient cyclization reactions, facilitating the construction of bioactive scaffolds under mild conditions. The compound exhibits good bench stability and is compatible with common functional groups, simplifying purification and enabling integration into multi-step synthetic sequences.

Synthesis

  • Route1

    References

    • Journal of the Chemical Society, Chemical Communications, , # 23 p. 1668 - 1669
  • Route2
    • null|null
      176243-28-0
    • ~74%
    • In-stock
      2-Hydroxyisophthalaldehyde|CS-W016326
      3328-69-6

    References

    • Zondervan, Charon; Van Den Beuken, Esther K.; Kooijman, Huub; Spek, Anthony L.; Feringa, Ben L. Tetrahedron Letters, 1997 , vol. 38, # 17 p. 3111 - 3114
  • Route3
    • 2,6-Dimethylphenyl acetate|CS-0364987
      876-98-2
    • ~29%
    • In-stock
      2-Hydroxyisophthalaldehyde|CS-W016326
      3328-69-6

    References

    • Deng, Jing; Li, Ning; Liu, Hongchuan; Zuo, Zhili; Liew, Oi Wah; Xu, Weijun; Chen, Gang; Tong, Xiankun; Tang, Wei; Zhu, Jin; Zuo, Jianping; Jiang, Hualiang; Yang, Cai-Guang; Li, Jian; Zhu, Weiliang Journal of Medicinal Chemistry, 2012 , vol. 55, # 14 p. 6278 - 6293

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   54.37
  • LogP   1.0172
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Hydroxyisophthalaldehyde sigma2-Hydroxyisophthalaldehyde manufacturer2-Hydroxyisophthalaldehyde price2-Hydroxyisophthalaldehyde structure2-Hydroxyisophthalaldehyde SDSbuy 2-Hydroxyisophthalaldehyde2-Hydroxyisophthalaldehyde supplier2-Hydroxyisophthalaldehyde uses2-Hydroxyisophthalaldehyde molecular weightprice of 2-Hydroxyisophthalaldehyde2-Hydroxyisophthalaldehyde chemical name formula of 2-Hydroxyisophthalaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label