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CS-W001157 4
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4-(Hydroxy(pyridin-2-yl)methyl)phenol

  • CAS No. 33455-95-7

  • Cat. No. CS-0163321
  • Molecule weight201.22
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Hydroxy(pyridin-2-yl)methyl)phenol|CS-0163321

Structure of 33455-95-7

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General Information

  • CAS No. 33455-95-7
  • Cat. No. CS-0163321
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₁NO₂
  • Molecular Weight 201.22
  • Synonym(s) 4-hydroxyphenyl(2-pyridyl) carbinol
  • SMILES OC1=CC=C(C(O)C2=NC=CC=C2)C=C1

Description

4-(Hydroxy(pyridin-2-yl)methyl)phenol features a phenolic hydroxyl group conjugated to a pyridinyl-methyl linker, enabling strong metal chelation and enhanced solubility in polar solvents. This bifunctional scaffold integrates aromatic rigidity with directional hydrogen bonding capacity, facilitating use in coordination chemistry and molecular recognition applications.

Application

4-(Hydroxy(pyridin-2-yl)methyl)phenol serves as a versatile building block for heterocyclic synthesis, enabling efficient access to biologically relevant scaffolds through palladium-catalyzed coupling and cyclization reactions. The phenolic hydroxyl group offers a handle for derivatization, while the pyridin-2-ylmethyl moiety provides orthogonal reactivity and metal coordination sites. Its bench-stable solid form facilitates handling and purification in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   1.8689
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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