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CS-W001157 4
Total: USD 88.00

6-CFDA

  • CAS No. 3348-03-6

  • Cat. No. CS-3853
  • Purity95+%
  • MDL No.MFCD00036871

*For research and further manufacturing use only, not for direct human use.

6-CFDA|CS-3853

Structure of 3348-03-6

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General Information

  • CAS No. 3348-03-6
  • Cat. No. CS-3853
  • Purity 95+%
  • MDL No. MFCD00036871
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₁₆O₉
  • Molecular Weight 460.39
  • Synonym(s) 6-Carboxyfluorescein diacetate
  • SMILES CC(OC1=CC=C(C2(O3)C4=CC(C(O)=O)=CC=C4C3=O)C(OC5=C2C=CC(OC(C)=O)=C5)=C1)=O

Description

6-CFDA delivers a robust, bench-stable fluorescent probe for real-time tracking in live-cell imaging. This boronate-functionalized derivative features enhanced membrane permeability and rapid hydrolysis to yield the active fluorescent species. Ideal for monitoring esterase activity and intracellular pH shifts under physiological conditions.

Application

6-CFDA serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized benzimidazole scaffolds. Its stability under standard reaction conditions and compatibility with diverse coupling protocols facilitate straightforward derivatization for medicinal chemistry applications. The molecule's defined electronic profile enhances regioselective transformations, making it a reliable reagent for constructing biologically relevant heterocyclic frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Computational Chemistry Data

  • TPSA   125.43
  • LogP   3.8034
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   3

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