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Structure of 33529-01-0
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1-Hexylimidazole features a hydrophobic hexyl chain appended to the imidazole core, enhancing solubility in nonpolar media while retaining the nitrogen heterocycle’s strong basicity and coordination capacity. This balance enables effective use as a stabilizing ligand in catalytic systems and a tunable additive in synthetic transformations requiring controlled basicity and lipophilicity.
1-Hexylimidazole serves as a versatile nitrogen heterocycle with enhanced solubility and reduced volatility compared to smaller imidazoles. It functions as a robust ligand in transition metal catalysis, particularly in Pd- and Ni-catalyzed cross-coupling reactions, where its steric and electronic profile promotes catalyst stability and turnover. The alkyl chain improves handling and purification, making it well-suited for bench-scale synthesis and scalable processes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: