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Structure of 335449-19-9
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(2-Iodoethyl)cyclopropane features a strained cyclopropyl ring fused to an iodoethyl tether, enabling efficient intramolecular cyclization. The iodide serves as a potent electrophilic handle for palladium-catalyzed cross-coupling reactions, while the cyclopropane moiety imparts unique conformational rigidity and enhanced reactivity in synthetic transformations. This combination delivers precise control over molecular architecture in complex scaffold construction.
(2-Iodoethyl)cyclopropane serves as a versatile alkylating agent in synthetic organic chemistry, enabling efficient functionalization of nucleophiles under mild conditions. Its cyclopropyl ring imparts unique steric and electronic properties that enhance regioselectivity in C–C bond formation. The iodide group exhibits high reactivity in palladium-catalyzed cross-coupling reactions and facilitates clean displacement by amines, thiols, and other soft nucleophiles. This compound demonstrates excellent bench stability and ease of purification, making it well-suited for use in the construction of bioactive heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H227-H302-H312-H315-H318-H332-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: