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Structure of 33866-05-6
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3-Chloro-4-(fluorosulfonyl)benzoic acid features a fluorosulfonyl group that enhances electrophilicity for efficient coupling reactions. This bench-stable, moisture-tolerant reagent integrates readily into synthetic workflows requiring sulfonate functionality. The para-chloro substitution provides steric and electronic control during derivatization.
3-Chloro-4-(fluorosulfonyl)benzoic acid serves as a versatile building block for constructing sulfonamide-containing heterocycles and bioactive scaffolds. The fluorosulfonyl group enables efficient displacement reactions, while the carboxylic acid facilitates amide coupling or salt formation. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314-H335
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Precautionary Statements : P260-P264-P271-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: