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Structure of 338795-36-1
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8-Chloro-3-(pyridin-4-yl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine features a fused triazolopyridine core bearing a chloro group at C8, a pyridin-4-yl substituent at C3, and a trifluoromethyl moiety at C6. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced metabolic stability and targeted binding affinity in kinase inhibition studies.
8-Chloro-3-(pyridin-4-yl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the pyridin-4-yl moiety enables metal-catalyzed coupling reactions. The chloro substituent provides a reliable site for nucleophilic displacement, facilitating diversification via SNAr processes. This compound exhibits excellent bench stability and compatibility with standard purification methods, making it a practical scaffold for high-throughput library synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: