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Structure of 3389-54-6
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Phenyl(pyrrolidin-1-yl)methanone features a pyrrolidinyl group attached to a carbonyl-linked phenyl ring, delivering high lipophilicity and enhanced membrane permeability. This structural motif enables efficient integration into bioactive scaffolds, particularly in medicinal chemistry campaigns targeting CNS-penetrant molecules. The compound exhibits bench-stable handling characteristics under standard conditions.
Phenyl(pyrrolidin-1-yl)methanone serves as a versatile benzoyl equivalent in synthetic organic chemistry, enabling efficient amide bond formation under mild conditions. Its pyrrolidine-derived acyl group exhibits favorable reactivity in nucleophilic acyl substitution, facilitating the construction of complex amides and heterocyclic scaffolds. The compound demonstrates bench stability, ease of handling, and compatibility with diverse functional groups, making it a practical choice for medicinal chemistry campaigns and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: