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CS-W001157 4
Total: USD 88.00

Boc-Ala-Osu

  • CAS No. 3392-05-0

  • Cat. No. CS-W012221
  • Purity≥95%
  • MDL No.MFCD00065974

*For research and further manufacturing use only, not for direct human use.

Boc-Ala-Osu|CS-W012221

Structure of 3392-05-0

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General Information

  • CAS No. 3392-05-0
  • Cat. No. CS-W012221
  • Purity ≥95%
  • MDL No. MFCD00065974
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈N₂O₆
  • Molecular Weight None
  • Synonym(s) Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
  • SMILES C[C@@H](C(ON1C(CCC1=O)=O)=O)NC(OC(C)(C)C)=O

Description

Boc-Ala-Osu delivers a protected alanine residue with enhanced stability and ease of handling in peptide synthesis. The Boc group ensures efficient deprotection under mild acidic conditions, while the Osu ester facilitates rapid coupling reactions. This combination streamlines N-terminal protection strategies in solid-phase and solution-phase workflows.

Application

Boc-Ala-Osu serves as a versatile amino acid building block for solid-phase peptide synthesis, enabling efficient incorporation of alanine residues with orthogonal protection. The Boc group provides stable Nα-protecting functionality, while the O-succinimidyl ester (Osu) moiety facilitates rapid coupling to primary amines under mild conditions. Its bench-stable nature and compatibility with standard deprotection protocols make it ideal for sequential peptide assembly and conjugation workflows.

Synthesis

  • Route1
    • In-stock
      Boc-L-Ala-OH|CS-W009232
      15761-38-3
    • null|null
      107960-02-1
    • ~91%
    • In-stock
      Boc-Ala-Osu|CS-W012221
      3392-05-0

    References

    • Societe Nationale des Poudres et Explosifs Patent: US4782164 A1, 1988 ;
  • Route2

    References

    • Lioux, Thierry; Busson, Roger; Rozenski, Jef; Nguyen-Disteche, Martine; Frere, Jean-Marie; Herdewijn, Piet Collection of Czechoslovak Chemical Communications, 2005 , vol. 70, # 10 p. 1615 - 1641
  • Route3
    • null|null
      16948-17-7
    • null|null
      90704-86-2
    • ~84%
    • In-stock
      Boc-Ala-Osu|CS-W012221
      3392-05-0

    References

    • Il'ina, A. V.; Davidovich, Yu. A.; Rogozhin, S. V.; Moiseenkov, A. M. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984 , vol. 33, p. 1067 - 1070 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984 , # 5 p. 1163 - 1165

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   102.01
  • LogP   0.5068
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   3

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