2,5-Dioxopyrrolidin-1-yl (tert-butoxycarbonyl)-L-valinate

Name: 2,5-Dioxopyrrolidin-1-yl (tert-butoxycarbonyl)-L-valinate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 3392-12-9
Cat. No. CS-W009916
Purity≥97%
MDL No.MFCD00037906

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,5-Dioxopyrrolidin-1-yl (tert-butoxycarbonyl)-L-valinate|CS-W009916

Structure of 3392-12-9

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This tert-butoxycarbonyl-protected valine derivative features a reactive dioxopyrrolidinyl leaving group, enabling efficient amide bond formation under mild conditions. The bulky tert-butyl carbamate moiety provides enhanced stability and ease of purification, while the hydrophobic valine side chain supports incorporation into peptide sequences with minimal steric interference.

Application

Boc-L-valine 2,5-dioxopyrrolidin-1-yl ester serves as a robust amino acid coupling agent, enabling efficient amide bond formation in peptide synthesis. The pyrrolidinone ester moiety ensures high reactivity with primary amines under mild conditions, while the tert-butoxycarbonyl (Boc) group provides stable protection of the α-amino function. This compound exhibits excellent bench stability, simplifies purification by precipitation, and is compatible with a broad range of functional groups, making it a reliable building block for fragment assembly and synthetic peptide workflows.

General Information

CAS No. 3392-12-9
Cat. No. CS-W009916
Purity ≥97%
MDL No. MFCD00037906
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₂₂N₂O₆
Molecular Weight 314.33
Synonym(s) tert-Butyl (S)-(1-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)-2-methylpropyl)carbamate
SMILES CC(C)[C@@H](C(ON1C(CCC1=O)=O)=O)NC(OC(C)(C)C)=O

Computational Chemistry Data

TPSA 102.01
LogP 1.1429
H_Acceptors 6
H_Donors 1
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H401
Precautionary Statements : P273-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Valine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

3392-12-9 sigma3392-12-9 manufacturer3392-12-9 price3392-12-9 structure3392-12-9 SDSbuy 3392-12-93392-12-9 supplier3392-12-9 uses3392-12-9 molecular weightprice of 3392-12-93392-12-9 chemical name formula of 3392-12-9

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,5-Dioxopyrrolidin-1-yl (tert-butoxycarbonyl)-L-valinate

CAS No. 3392-12-9

Recommended Products