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CS-W001157 4
Total: USD 88.00

2,2,2-Trifluoro-1-(piperidin-1-yl)ethan-1-one

  • CAS No. 340-07-8

  • Cat. No. CS-0143336
  • Purity≥98%
  • MDL No.MFCD00466213

*For research and further manufacturing use only, not for direct human use.

2,2,2-Trifluoro-1-(piperidin-1-yl)ethan-1-one|CS-0143336

Structure of 340-07-8

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General Information

  • CAS No. 340-07-8
  • Cat. No. CS-0143336
  • Purity ≥98%
  • MDL No. MFCD00466213
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀F₃NO
  • Molecular Weight 181.16
  • Synonym(s) N-(Trifluoromethylacetyl)piperidine
  • SMILES O=C(N1CCCCC1)C(F)(F)F

Application

2,2,2-Trifluoro-1-(piperidin-1-yl)ethan-1-one serves as a versatile acylating agent in synthetic organic chemistry, enabling efficient introduction of trifluoromethyl ketone motifs. Its reactivity facilitates nucleophilic acyl substitution with amines and alcohols under mild conditions, offering excellent functional group tolerance and bench stability. The piperidine moiety enhances solubility and supports downstream transformations, making it valuable for constructing fluorinated heterocycles and medicinal chemistry scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H300-H319-H400
Precautionary Statements : P264-P270-P273-P280-P330-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.31
  • LogP   1.5612
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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