HDAC4 ligand-2

Name: HDAC4 ligand-2
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 340736-76-7
Cat. No. CS-0097932
Molecule weight258.15
Purity≥97%
MDL No.MFCD16659622

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 340736-76-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 340736-76-7
Cat. No. CS-0097932
Purity ≥97%
MDL No. MFCD16659622
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₅F₃N₂O₃
Molecular Weight 258.15
Synonym(s) None
SMILES O=C(C1=CC=C(C=C1)C2=NOC(C(F)(F)F)=N2)O

Description

This trifluoromethyl-substituted oxadiazole-carboxylic acid integrates a polar, electron-deficient heterocycle with a benzoic acid handle, enabling direct conjugation in bioconjugation and medicinal chemistry. The robust oxadiazole ring enhances metabolic stability while the para-carboxylate supports derivatization under standard coupling conditions.

Application

4-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid serves as a versatile building block for bioactive heterocycles, enabling efficient access to pharmacologically relevant scaffolds. The trifluoromethyl oxadiazole moiety imparts enhanced metabolic stability and lipophilicity, while the carboxylic acid group facilitates direct coupling reactions or derivatization. Its bench-stable nature and compatibility with standard peptide and cross-coupling protocols make it ideal for medicinal chemistry campaigns targeting CNS and oncology applications.

Synthesis

Route1
- 23610-05-1
- 407-25-0
- ~75%
- In-stock
  
  340736-76-7
References
- NOVARTIS AG; HEBACH, Christina; JOLY, Emilie; KALLEN, Joerg; TERNOIS, James Gilbert; TINTELNOT-BLOMLEY, Marina Patent: WO2013/8162 A1, 2013 ; Location in patent: Page/Page column 63 ;
Route2
- 340736-74-5
- ~%
- In-stock
  
  340736-76-7
References
- Chemical and Pharmaceutical Bulletin, , vol. 49, # 3 p. 268 - 277
Route3
- 407-25-0
- 23610-05-1
- ~54%
- In-stock
  
  340736-76-7
References
- Liu, Kun; Lu, Hong; Hou, Ling; Qi, Zhi; Teixeira, Catia; Barbault, Florent; Fan, Bo-Tao; Liu, Shuwen; Jiang, Shibo; Xie, Lan Journal of Medicinal Chemistry, 2008 , vol. 51, # 24 p. 7843 - 7854

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 76.22
LogP 2.4536
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic heterocycle compounds Oxadiazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

HDAC4 ligand-2 sigmaHDAC4 ligand-2 manufacturerHDAC4 ligand-2 priceHDAC4 ligand-2 structureHDAC4 ligand-2 SDSbuy HDAC4 ligand-2HDAC4 ligand-2 supplierHDAC4 ligand-2 usesHDAC4 ligand-2 molecular weightprice of HDAC4 ligand-2HDAC4 ligand-2 chemical name formula of HDAC4 ligand-2

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

HDAC4 ligand-2

CAS No. 340736-76-7

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words